Welcome!
This
site will tell you about the group as it currently stands, the
chemistry that we do and how to contact us if you are interested in
applying.
News!! May 2018 Congratulations to (now Dr) Younes Fegheh-Hassanpour for passing his viva! A
second synthesis of 6,7-DDSQ H5 is now online in Chem Comm! The
synthesis, exploiting alkene protection against acid using a bromide
substituent, was initiated by Hamad and completed by Hasanain. April 2018 Younes
and past Part II student Faisal's work on the ozonolysis of unsaturated
tosylhydrazones as a direct approach to diazocarbonyl compounds is now online.
September 2017
Congruence
Between Computation and Experiment: Yifei, Andrew and co-workers collaborative
study with Kelvin Jackson and Rob Paton, on asymmetric induction in alkylations
of chiral tropane-derived enamines, is online and Open Access at JOC.
Aubert's
collaborative work with Oxford oncologists, on the cytotoxin Aruncin B and
analogues, is online and Open Access
at Chemistry A European Journal.
May 2017
Congratulations to (now Dr) Aubert Ribaucourt for passing his
viva! Aubert is moving on to a postdoc with Josh Pierce at NC State
University.
March 2017
6,7-DDSQ H5 made! Younes
completes a long-standing synthetic objective in the Hodgson group, and the
work has subsequently been published and is Open Access.
September 2016
The group welcomes new
graduate student Pascal and new Part II student Faisal.
Aubert receives a prize for
the best talk at the 3rd annual OxIOSCR conference in Oxford.
August 2016
Younes and Aubert attended
the 252nd National Meeting of the ACS in Philadelphia, where they presented
posters on their research.
Aubert's work on the
synthesis and structural revision of the cytotoxin aruncin B is online at
Organic Letters.
June 2016
A review on "recent
applications in natural product synthesis of dihydrofuran and -pyran formation
by ring-closing alkene metathesis”, cowritten with 5 of the current first year
EPSRC CDT SBM cohort and Aubert, is online and Open Access
at Organic & Biomolecular Chemistry. The review has been highlighted
on the front cover of 14(25) and as
a ‘Hot Article'.
March & April 2016
Congratulations
to Aubert, for winning the Chemistry World Poster Prize at
the 19th International Symposium on Advancing the Chemical Sciences: Challenges
in Organic Chemistry, held on 20-23 March in Irvine, USA. Aubert was also
selected to present his work at the SCI 27th Regional (Southern UK) PG
symposium on Organic Chemistry, held at Imperial College in London on 19th
April.
January 2016 The group welcomes new graduate student Hasanain and postdoc Yifei. September 2015
The group welcomes new Part
II student JP.
Aubert presents a talk, and
receives a prize for his poster, at the 2nd annual OxIOSCR conference in
Oxford.
Claire’s work, in
collaboration with computational and NMR chemists at Oxford, to understand the
origin of regiodivergence in lithiation–electrophilic substitution of
substituted azetidines, is online and Open Access at JOC as a Featured Article.
Past postgraduate
Saifullah’s invited review on the “Hodgson cyclopropanation reaction”, is
online at Current Organic Chemistry, and will be part of a
Special Thematic Issue on Selective Metal Carbene Reactions in Small
Cyclic Compounds Construction.
May 2015 Congratulations to (now Dr)
Claire Mortimer for passing her viva! Claire is moving on to a synthetic
chemistry position at BioFocus (Charles River Laboratories), Chesterford
Research Park.
January 2015 Johannes’
and Chris’ work - in collaboration with Tim Claridge and Barbara Odell, and
Ilya Kuprov (at Southampton) - to understand the origins of apparently
anomalous cross-peaks in 2D 1H NOESY spectra of C-substituted aziridines, is online and Open
Access at Angewandte Chemie.
Claire's
research showing a method for alpha-electrophile incorporation on
azetidine, in which the t-Butoxythiocarbonyl (Botc) group, the
long-neglected thiocarbonyl analogue of Boc, plays a crucial role, is online and Open Access at Organic Letters. October
2014
Congratulations
to Claire who was awarded a prize for her talk at the Department's DPhil
Symposium.
The
group welcomes new postgraduate student Younes and Erasmus+ student Heinrich.
Stan's,
past part II Jade’s and summer student Ziga's approach to the anti-HIV agent
hyperolactone C and analogues using consecutive oxonium ylide
formation-sigmatropic rearrangement (proceeding with high selectivity between
subtly different acetal oxygen atoms) and acid-catalysed
elimination-lactonisation, is online at
JOC.
An
updated review (with past post doc Emmanuel) on Oxiranes and Oxirenes:
Fused-ring Derivatives (Comprehensive Heterocyclic Chemistry III), is now online at
Elsevier Reference Module in Chemistry, Molecular Sciences and Chemical
Engineering.
September 2014
The group welcomes new Part II student Ben.
Claire presents her work as a lecture at the RSC
Heterocyclic and Synthesis Group Annual Postgraduate Symposium, at Vertex
Pharmaceuticals.
July 2014
Congratulations
to (now Dr) Chris Pearson, currently employed as a senior chemist in discovery
chemistry at Evotec, for passing his viva! June 2014
The group welcomes undergraduate summer student Chris Hall.
March
2014
Andrew's
review, on Methods for Direct Generation of α-Alkyl-Substituted Aldehydes,
is online at Tetrahedron
and on the cover of 70(13).
January 2014
Chris' and visiting
postgraduate Madiha's research showing a new and concise entry to valuable
4-membered azacycles, by in situ generation and alpha-functionalisation of the
strained azetine system, is online and Open Access at Organic Letters.
October 2013
Congratulations to Chris who was awarded a prize for his talk at the Department's DPhil Symposium. Chris also recently presented his work at the AstraZeneca Collaborations Conference at Alderley Park, Macclesfield.
The group welcomes new graduate student Aubert Ribaucourt.
July 2013
Elena's, Stan's, and past part II Sophie's approach to the anti-HIV agent hyperolactone C and analogues using
late stage conjugate addition on an oxonium ylide-derived spirofuranone, is online at Organic & Biomolecular Chemistry.
June 2013
The group welcomes visiting postgraduate students Iram and Madiha, and undergraduate summer students Ziga and Glenn.
May 2013
Congratulations to Andrew for passing his viva!
February 2013
A decade in the making, David, Agnès and Sengo's review on Cycloadditions of Carbonyl Ylides Derived from Diazocarbonyl Compounds is published in Organic Reactions.
With ~300 pages of tables organised by substrate type
and detailing all known reactions, this work provides a definitive
review of these cycloadditions.
January 2013
Andrew's collaborative study with Rob Paton, on asymmetric induction
in alkylations of chiral tropane- and homotropane-derived enamines, is online at JOC.
Chris' azetidine study, showing that electrophile incorporation with high levels of diastereocontrol is
possible, is online at JOC.
October 2012
Following his graduate and postdoctoral studies in the Hodgson
group, Tanzeel has started a PDRA position with Willie Motherwell at
UCL.
September 2012
The group welcomes Elena from Spain as she starts a postdoc for the next 6 months.
August 2012
Rosannes work on a convergent approach to conjugated 1,2-disubstituted E-allylic alcohols from two aldehydes is online at Organic & Biomolecular Chemistry.
Congratulations to Rosanne for passing her MSc(Res) viva! Rosanne is moving on to further graduate studies with Ray Andersen
at UBC, Canada.
Saifullah's work on syn-B-hydroxyallylic silanes from terminal epoxide
a-lithiation-silyation and alkenylation, and application towards the
lytophilippines, is online at Organic Letters.
May 2012
Congratulations to Saifullah for passing his viva!
Eric's synthesis of the anti-trypanosomal agent hydroxyanthecotulide using Cr(II)-catalysed allylation is online at Chemical Communications and highlighted in the ChemComm blog.
January 2012
Congratulations to Eric for passing his viva, and for securing a
prestigious Novartis Presidential Postdoctoral Fellowship which will be
carried out at their site in Horsham and at University of California
Berkeley, in collaboration with Dean Toste.
October 2011
Eric's work on the first synthesis of (+)-anthecotulide, by a
protecting group free strategy using catalytic enantioselective enyne
and Meyer-Schuster rearrangements, is online at Organic Letters.
July 2011
Stan's asymmetric synthesis of the anti-HIV agent (-)-hyperlactone C using oxonium ylide formation-rearrangement is now online at Chemistry A European Journal
April 2011
Congratulations to Tanzeel for passing his viva!
Eric gives a talk on
his work at the ACS 241st National Meeting in Anaheim, and part of his
studies on α-methylene-γ-butyrolactones is online at Organic Letters
October 2010
The group welcomes new postgraduates Claire, Chris, and Rosanne, and Part II students Sophie and Matthew.
September 2010
Tanzeel's work on a convergent and highly stereoselective method for the synthesis of trisubstituted allylic esters is online at Organic Letters
August 2010
Eric presents a poster on his work at the 3rd EuCheMS Chemistry Congress in Nürnberg, Germany.
July 2010
The Group welcomes visiting postgraduate Serdar Sezer, joining for a year from Turkey.
Carol's collaborative study with Jonathan Goodman at Cambridge, on the squalestatins involving a carbonyl ylide cycloaddition-rearrangement strategy, is online at Org. Biomol. Chem.
May 2010
Ruth's (and past part II Tom's) total synthesis of the Aristotelia
alkaloid peduncularine, involving an efficient Lewis acid induced
novel nitrogen-driven rearrangement iminiun-trapping cascade, is online at Organic Letters.
Naeem's collaborative study with Joann Um and K. Houk at
UCLA on the origins of asymmetric induction in alkylations of his
chiral piperidine enamines, is online at Chemistry-A European Journal.
March 2010
Preliminary studies by Johannes on a method for
the α-incorporation of electrophiles onto azetidine, including the
first example of an enantioselective electrophilic substitution on
a four-membered ring, are online at Angewandte
January 2010
Saifullah's work on cubebol syntheses by intramolecular cyclopropanation of unsaturated α-lithiated epoxides is online at JOC, and will be the Cover Article of Issue 7.
December 2009
Johannes passes viva and will start postdoctoral studies in January with Frank Glorius at Munster, Germany.
October 2009
Saifullah awarded a prize at the annual Oxford Organic Chemistry
Poster Session for second year postgraduates, sponsored by Pfizer.
September 2009
Andrew awarded a Lilly-sponsored prize from the Oxford Organic
Chemistry Sub-Department, for excellence in the first year of
postgraduate study.
Webmaster: Pascal Delany (pascal.delany@chem.ox.ac.uk) |